Cefmetazole sodium( —— )

Catalog No. M15067 CAS No. 56796-39-5

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Product Name

Cefmetazole sodium
Note

Research use only, not for human use.
Brief Description

Cefmetazole sodium is a semisynthetic cephamycin antibiotic.
Description

Cefmetazole sodium is a semisynthetic cephamycin antibiotic. Target: Antibacterial Cefmetazole sodium has a broad spectrum of activity comparable to that of the second-generation cephalosporins, covering gram-positive, gram-negative, and anaerobic bacteria.(In Vitro):Cefmetazole sodium (Sodium cefmetazole) has antibiotic affinity to?S. aureus?with a MIC value of 1.0 mg/L and has affinity for PBP1, PBP2 and PBP3 with IC50?values of ≤0.3, 0.109 and 0.494 mg/L.(In Vivo):Cefmetazole sodium (Sodium cefmetazole) (100 mg/kg; i.h.; twice a day, for 7 days; male ICR mice) alters gut bacterial flora.
In Vitro

Cefmetazole sodium (Sodium cefmetazole) has antibiotic affinity to S. aureus with a MIC value of 1.0 mg/L and has affinity for PBP1, PBP2 and PBP3 with IC50 values of ≤0.3, 0.109 and 0.494 mg/L.
In Vivo

Cefmetazole sodium (Sodium cefmetazole) (100 mg/kg; i.h.; twice a day, for 7 days; male ICR mice) alters gut bacterial flora. Animal Model:Male ICR mice Dosage:100 mg/kg Administration:Subcutaneous injection; twice a day, for 7 days Result:Reduced Peyer's patch (PP) lymphocyte cell numbers while decreased bacterial numbers in the small intestine.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Infection
Indication

——

CAS Number

56796-39-5
Formula Weight

493.52
Molecular Formula

C15H16N7NaO5S3
Purity

>98% (HPLC)
Solubility

DMSO: 39mg/mL
SMILES

CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSCC#N)OC)SC2)C(=O)[O-].[Na+]
Chemical Name

——

1.Inagaki K, et al. J Parenter Sci Technol. 1993 Jan-Feb;47(1):35-9.

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